Depression Treatment
Depression is more than low mood — it is a treatable medical condition that can affect how you think, feel, sleep, work and relate to the people around you.
At Alexmed in Didsbury, Manchester, consultant psychiatrist Dr Micheal Kurkar provides private, evidence-based assessment and treatment for depression, including options for people who have not improved with previous antidepressants.
You do not need a GP referral to book. If you are struggling and would like a specialist opinion, you can arrange an appointment or call 07376 079877.
What is depression
Depression (clinical depression, or major depressive disorder) is a common mental health condition that causes persistent low mood and a loss of interest or pleasure in daily life for two weeks or longer. It ranges from mild to severe and often occurs alongside anxiety. With the right treatment, most people recover or see a meaningful reduction in symptoms.
Signs and symptoms of depression
Depression affects mood, thinking and the body. You may recognise several of the following, most of the day, nearly every day:
- Persistent sadness, low mood or a sense of emptiness
- Loss of interest or enjoyment in activities you used to like
- Fatigue, low energy or feeling slowed down
- Changes in sleep — difficulty sleeping or sleeping too much
- Changes in appetite or weight
- Difficulty concentrating, remembering or making decisions
- Feelings of worthlessness, guilt or hopelessness
- Irritability, tearfulness or restlessness
- Loss of libido
- Thoughts of self-harm, death or suicide
* If you are in crisis or thinking about harming yourself, do not wait for an appointment. Call 999, contact NHS 111 option 2 for mental health, or call the Samaritans free on 116 123, any time, day or night.
What causes depression?
Depression usually results from a combination of factors rather than a single cause, including genetic and family history, brain chemistry, long-term stress, bereavement or loss, physical illness, hormonal changes, and alcohol or drug use.
Understanding the factors relevant to you is part of a thorough psychiatric assessment and helps shape the right treatment plan.
Depression treatment options at Alexmed
There is no single “best” treatment for everyone. Dr Kurkar tailors a plan to the type and severity of your depression, your history, and your preferences. Options may include:
Psychiatric assessment and diagnosis
Effective treatment starts with an accurate diagnosis. A full psychiatric assessment clarifies whether your symptoms are due to depression, a related condition such as bipolar disorder or anxiety, or a physical cause — so treatment is targeted rather than trial and error.
Medication review and optimisation
Antidepressants can be highly effective for moderate to severe depression. If you are already taking medication that is not working, Dr Kurkar can review your diagnosis, dose and choice of medication, and adjust or switch treatment safely where appropriate.
Psychological therapy
Talking therapies such as cognitive behavioural therapy (CBT) are recommended for many people with depression, either on their own or alongside medication. Where therapy is indicated, we can advise on and signpost suitable options.
TMS therapy for treatment-resistant depression
If depression has not responded to two or more antidepressants, you may have treatment-resistant depression. Transcranial Magnetic Stimulation (TMS) is a non-invasive, medication-free treatment recommended by NICE for treatment-resistant depression. It uses magnetic pulses to stimulate areas of the brain involved in mood regulation, and does not require anaesthetic or sedation. Dr Kurkar was a principal investigator on the BRIGhTMIND TMS trial.
Lifestyle and ongoing support
Sleep, physical activity, reducing alcohol and structured routines all support recovery. Your plan includes practical guidance and clear follow-up so progress can be reviewed and treatment adjusted.
Treatment-resistant depression
Around a third of people with depression do not fully respond to the first treatments they try. This is known as treatment-resistant depression, and it does not mean your depression cannot be treated — it means a more specialist approach is needed. Options include reviewing the original diagnosis, adjusting or combining medications, and considering TMS therapy. As a TMS specialist, Dr Kurkar can advise whether it may be suitable for you.
Why choose Alexmed for depression treatment
- Consultant psychiatrist-led care — assessment and treatment by Dr Micheal Kurkar, Consultant Psychiatrist, registered with the General Medical Council (GMC #6061661).
- Specialist in treatment-resistant depression — including NICE-recommended TMS therapy on site.
- No GP referral required — refer yourself directly.
- Prompt private appointments — flexible times without long NHS waits.
- Convenient Manchester location — in Didsbury, serving Manchester and the surrounding areas.
Book a depression assessment in Manchester
If depression is affecting your life, specialist help is available. Book a private consultation with Dr Micheal Kurkar at Alexmed in Didsbury, Manchester.
Frequently asked questions
Do I need a GP referral to be treated for depression?
No. Alexmed is a private clinic and you can refer yourself directly. Simply book an appointment online or by phone.
How is depression diagnosed?
Through a clinical assessment with a psychiatrist, who reviews your symptoms, history and any physical or lifestyle factors, and rules out other conditions before recommending treatment.
How long does depression treatment take to work?
It varies. Antidepressants typically take four to six weeks to show their full effect, while talking therapies and TMS follow their own course. Dr Kurkar reviews your progress and adjusts treatment as needed.
What if antidepressants haven't worked for me?
You may have treatment-resistant depression. Options include reviewing your diagnosis and medication or considering TMS therapy, a NICE-recommended, non-invasive treatment available at Alexmed.
Is TMS therapy available for depression at Alexmed?
Yes. TMS is offered for treatment-resistant depression. Learn more on the TMS therapy page.
How much does depression treatment cost?
Fees depend on the assessment and treatment plan. Please contact the clinic for current fees before your appointment.